HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 58662444, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-ethyl-6,8-dimethyl-4-oxo-3,4-dihydro-2H-[1,7]naphthyridine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester | HCID 58662434 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 58662444 | HCID 58662444 | — |
Reaction Steps
This compound can be obtained by reacting a solution of 2-ethyl-6,8-dimethyl-4-oxo-3,4-dihydro-2H-[1,7]naphthyridine-1,3-dicarboxylic acid 1-benzyl ester 3-methyl ester, in ethanol, with 2N NaOH at reflux temperature, for a time period from about 0.5 h to about 2 h, followed by a typical workup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700774B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-143515e048894d4cafb4a322cc8274a5 |
| Source note | uspto-grants-2010_04 |