HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-nitroanisole → 5-Methyl-3-(3-methoxy-4-nitrophenyloxy)pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-nitroanisole | HCID 81110 | — |
| Reactant | 3H-Pyrazol-3-one, 2,4-dihydro-5-methyl- | HCID 319771 | — |
| Product | 5-Methyl-3-(3-methoxy-4-nitrophenyloxy)pyrazole | HCID 17862331 | 13.2% |
Reaction Steps
Reaction of 3-hydroxy-5-methylpyrazole with 5-chloro-2-nitroanisole was carried out in the same manner as Example 3, to give a yellow viscous substance of 5-methyl-3-(3-methoxy-4-nitrophenyloxy)pyrazole (yield: 13.2%). 1H-NMR (CDCl3, TMS, ppm): δ 2.34 (s, 3H), 3.93 (s, 3H), 5.74 (s, 1H), 6.70 (dd, J=2.4 and 9.1 Hz, 1H), 6.85 (d, J=2.4 Hz, 1H), 7.95 (d, J=9.1 Hz, 1H), 9.45 (br s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700786B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-55d4de3d0321412caa289c0ea8b8773c |
| Source note | uspto-grants-2010_04 |