Ethyl isocyanate → HCID 17862444, compound

HRID 644874Notes

Reaction equation

HRID 644874 reaction equation
[CH3:1][C:2]1[NH:6][N:5]=[C:4]([O:7][C:8]2[CH:13]=[C:12]([CH3:14])[C:11]([N+:15]([O-:17])=[O:16])=[CH:10][N:9]=2)[CH:3]=1.[CH2:18]([N:20]=[C:21]=[O:22])[CH3:19]>C(N(CC)CC)C>[CH2:18]([NH:20][C:21]([N:6]1[C:2]([CH3:1])=[CH:3][C:4]([O:7][C:8]2[CH:13]=[C:12]([CH3:14])[C:11]([N+:15]([O-:17])=[O:16])=[CH:10][N:9]=2)=[N:5]1)=[O:22])[CH3:19]

Participants

4

Reactant 2

HCID 8022Ethyl isocyanateHCID 17862357HCID 17862357, compound

Product 1

HCID 17862444HCID 17862444, compoundYield 19.3%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Reaction of 5-methyl-3-(4-methyl-5-nitropyridin-2-yloxy)pyrazole with ethyl isocyanate was carried out in the presence of triethylamine in the same manner as in Example 130, to give a yellow viscous substance of N-ethyl-5-methyl-3-(4-methyl-5-nitropyridin-2-yloxy)pyrazole-1-carboxamide (yield: 19.3%). 1H-NMR (CDCl3, TMS, ppm): δ 1.23 (t, J=7.3 Hz, 3H), 2.65 (d, J=0.7 Hz, 3H), 2.70 (s, 3H), 3.40 (dq, J=5.9 and 7.3 Hz, 2H), 6.03 (q, J=0.7 Hz, 1H), 6.95 (s, 1H), 6.99 (br s, 1H), 8.92 (s, 1H).

Sources & evidence

ORD record
ord-a44d3f9774f74f12a3f16e2983c03279
Source dataset
uspto-grants-2010_04
Patent number
US07700786B2

Reaction notes

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