反应详情

温度

60 °C

The 4-(hexyloxy)phenyl 4-(benzyloxy)benzoate obtained as described above (5.0 g, 12.4 mmol) and palladium on carbon (2.5 g in the wet state) were placed in a sealed container under a nitrogen atmosphere, and dehydrated THF was slowly added thereto. Then, 28 mL of 1,4-cyclohexadiene was carefully and slowly added thereto dropwise, while heating at 60° C. and stirring. After the addition, the mixture was further stirred for additional 3 hours at 60° C. After the mixture was cooled to room temperature, the mixture was filtered through Celite and the solvents were removed by distillation. Thereby, a white solid compound, 4-(hexyloxy)phenyl 4-hydroxybenzoate (3.8 g) was obtained.

1. additionwas slowly added
2. additionslowly added
3. additionAfter the addition
4. stirringthe mixture was further stirred for additional 3 hours at 60° C
5. temperatureAfter the mixture was cooled to room temperature
6. filtrationthe mixture was filtered through Celite
7. customthe solvents were removed by distillation