N,N-Dimethyl-1,3-propanediamine → HCID 86718958, compound

Participants

Reaction Conditions

Reaction Steps

To 1,2-dichloroethane (130 ml) were added Nα-carboxy-Nε-benzyloxycarbonyl-L-lysine anhydride (4.02 g, 13.12 mmol) and N-carboxy-γ-methyl-L-glutamic acid anhydride (2.46 g, 13.12 mmol), N,N-dimethyl-1,3-propanediamine (32.78 μl, 0.262 mmol) was added as an initiator, and the mixture was stirred at 25° C. for 1 day to give a γ-methyl-L-glutamic acid/Nε-benzyloxycarbonyl-L-lysine copolymer. The weight average molecular weight, Mw, of the copolymer was measured by Measurement Method 1 described below. In addition, the composition of the copolymer was measured by Measurement Method 2 described below.

Provenance & Evidence