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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645527Generated: November 1, 2026

HCID 16070101, compound → HCID 16725685, compound

https://huagongshe.com/reaction/645527

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 16070101HCID 16070101—
ReactantHCID 58880220HCID 58880220—
ReactantHCID 68676243HCID 68676243—
ProductHCID 16725685HCID 16725685—

Reaction Steps

By a similar procedure to the preparation of the compound of Example 1, {4-Amino-2-[4-(3-morpholin-4-yl-propane-1-sulfonyl)-cyclohexylamino]-pyrimidin-5-yl}(2,3-difluoro-6-methoxy-phenyl)-methanethione was made from {4-Amino-2-[4-(3-morpholin-4-yl-propane-1-sulfonyl)-cyclohexylamino]-pyrimidin-5-yl}(2,3-difluoro-6-methoxy-phenyl)-methanone (prepared in accordance with US 2004/0162303 A1, 60 mg). LC/MS (m+H)+: 570.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705009B2
Source datasetuspto-grants-2010_04
ORD IDord-9dda29d3da5b42bfb87c0fb8e5557618
Source noteuspto-grants-2010_04