Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645547Generated: October 27, 2026

1-Methyl-3-pyrrolidinol → 2-((1-Methylpyrrolidin-3-yl)oxy)nicotinonitrile

https://huagongshe.com/reaction/645547

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-3-pyrrolidinolHCID 93074—
Reactant3-Cyano-2-fluoropyridineHCID 2783254—
Product2-((1-Methylpyrrolidin-3-yl)oxy)nicotinonitrileHCID 68585106—

Reaction Steps

2-Fluoro-nicotinonitrile was reacted with 1-methyl-pyrrolidin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 204 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07704997B1
Source datasetuspto-grants-2010_04
ORD IDord-7bbc87c78a554a1c89b8120bf5cdbc27
Source noteuspto-grants-2010_04