Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroacetaldehyde → HCID 178518393, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroacetaldehyde | HCID 33 | — |
| 반응물 | 6-Aminouracil | HCID 70120 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 178518393 | HCID 178518393 | 81% |
반응 단계
To a suspension of 6-aminouracil (15 g, 0.118 mol) in H2O (600 mL) was added sodium acetate (NaOAc) (15 g, 0.183 mol) and chloroethanal (ClCH2CHO) (50% in H2O, 30 mL). The mixture was heated at reflux for 4 h and then cooled to room temperature. The resulting dark brown precipitates were collected by filtration to afford crude 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol (14.4 g, 81% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07705004B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-b01a04c2081f4385a7d77e841ea49ad2 |
| 출처 메모 | uspto-grants-2010_04 |