Sodium Hydroxide → HCID 13726791, compound

Participants

Reaction Steps

A mixture of 7.0 g (0.0264 mol) of product of Example 3, 30 ml of 10% sodium hydroxide and 10 ml of methanol was held at reflux for 18 hours, cooled and extracted with ether. The aqueous layer was made acidic and the precipitate was collected and dissolved in ether. The ether solution was dried and mixture was concentrated. The residual solid was recrystallized from hexane-ether to give 5.5 g (83%) of solid, mp 194°-197.5° C.

Provenance & Evidence