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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 645774Generated: October 30, 2026

Ethanesulfonyl chloride → 1-(Ethanesulfonyl)piperazine

https://huagongshe.com/reaction/645774

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanesulfonyl chlorideHCID 11667—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant(3,5-Dimethylisoxazol-4-yl)(piperazin-1-yl)methanoneHCID 28776588—
Product1-(Ethanesulfonyl)piperazineHCID 415294—

Reaction Steps

Ethanesulfonyl-piperazine was prepared from 1-tert-butyloxycarbonyl-piperazine and ethylsulfonyl chloride in an analogous manner as described for the preparation of (3,5-dimethyl-isoxazol-4-yl)-piperazin-1-yl-methanone in example 41.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705007B2
Source datasetuspto-grants-2010_04
ORD IDord-c1b597e0535b463d87593649524fd503
Source noteuspto-grants-2010_04