N-bromobutanimide → HCID 59264639, compound

Participants

Reaction Steps

NBS (1.6 g, 9.34 mmol) was added in several small portions to a magnetically stirred solution of 1-(2,4-dichloro-phenyl)-4-methyl-5-selenophen-2-yl-1H-pyrazole-3-carboxylic acid ethyl ester (2.0 g, 4.67 mmol) in acetonitrile at 0° C. The resulting mixture was stirred at room temperature for 48 h. The precipitate was filtered out, washed with saturated aqueous sodium sulfite and cold water, and then dried under vacuum to give the desired compound (2.2 g, 92%) as a white solid.

Provenance & Evidence