HRID646055

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID240

Benzaldehyde

C7H6O

HCID68580721

未命名化合物

HCID68580747

未命名化合物

PRODUCTS

生成物

结构：CC(=O)NC(C)(C)Cc1c(C(C2=C(O)C(C)(Cc3ccccc3)C2=O)c2ccccc2)[nH]c2cc(C)ccc12

HCID59264916

未命名化合物

PROCEDURE

实验过程

Using general procedure C, 2-benzyl-2-methyl-cyclobutane-1,3-dione (Lit. 1) was reacted with benzaldehyde and N-[1,1-dimethyl-2-(6-methyl-1H-indol-3-yl)-ethyl]-acetamide (from Example 1.2) to give the title compound as a red solid. MS: 519.5 ([M−H]−).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c621a3af995646a8a3fed08da4353e02
来源数据集: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07705034B2
来源说明: uspto-grants-2010_04

反应 SMILES

[CH2:1]([C:8]1([CH3:14])[C:11](=[O:12])[CH2:10][C:9]1=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:15](=O)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[CH3:23][C:24]([NH:37][C:38](=[O:40])[CH3:39])([CH3:36])[CH2:25][C:26]1[C:34]2[C:29](=[CH:30][C:31]([CH3:35])=[CH:32][CH:33]=2)[NH:28][CH:27]=1>>[CH2:1]([C:8]1([CH3:14])[C:9](=[O:13])[C:10]([CH:15]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:27]2[NH:28][C:29]3[C:34]([C:26]=2[CH2:25][C:24]([NH:37][C:38](=[O:40])[CH3:39])([CH3:23])[CH3:36])=[CH:33][CH:32]=[C:31]([CH3:35])[CH:30]=3)=[C:11]1[OH:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1