HRID646056

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID240

Benzaldehyde

C7H6O

HCID68580747

未命名化合物

HCID68581027

未命名化合物

PRODUCTS

生成物

结构：CC(=O)NC(C)(C)Cc1c(C(C2=C(O)C(C)(c3ccccc3)C2=O)c2ccccc2)[nH]c2cc(C)ccc12

HCID25050877

未命名化合物

PROCEDURE

实验过程

Using general procedure C, 2-methyl-2-phenyl-cyclobutane-1,3-dione (Lit. 1) was reacted with benzaldehyde and N-[1,1-dimethyl-2-(6-methyl-1H-indol-3-yl)-ethyl]-acetamide (from Example 1.2) to give the title compound as a pale yellow solid. MS: 505.5 ([M−H]−).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6eb506636719462385ca44d02d69a565
来源数据集: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07705034B2
来源说明: uspto-grants-2010_04

反应 SMILES

[CH3:1][C:2]1([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:6])[CH2:4][C:3]1=[O:7].[CH:14](=O)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.[CH3:22][C:23]([NH:36][C:37](=[O:39])[CH3:38])([CH3:35])[CH2:24][C:25]1[C:33]2[C:28](=[CH:29][C:30]([CH3:34])=[CH:31][CH:32]=2)[NH:27][CH:26]=1>>[OH:6][C:5]1[C:2]([CH3:1])([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:3](=[O:7])[C:4]=1[CH:14]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:26]1[NH:27][C:28]2[C:33]([C:25]=1[CH2:24][C:23]([NH:36][C:37](=[O:39])[CH3:38])([CH3:22])[CH3:35])=[CH:32][CH:31]=[C:30]([CH3:34])[CH:29]=2