Benzaldehyde → (5-Methyl-benzo[b]thiophen-2-yl)-phenyl-methanol
Reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]2[S:6][CH:7]=[CH:8][C:4]=2[CH:3]=1.[CH:11](=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]2[S:6][C:7]([CH:11]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[OH:18])=[CH:8][C:4]=2[CH:3]=1Participants
3
Procedure
Using general procedure B, 5-methyl-benzo[b]thiophene was reacted with benzaldehyde to give (5-methyl-benzo[b]thiophen-2-yl)-phenyl-methanol as a colorless solid. MS: 237.1 ([M+H—H2O]+).
Sources & evidence
- ORD record
- ord-48998dac7cc24315ac4c475270570771
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07705034B2
Reaction notes
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