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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646108Generated: October 30, 2026

4-Bromophenol → HCID 65457361, compound

https://huagongshe.com/reaction/646108

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromophenolHCID 7808—
ReactantSodium HydroxideHCID 14798—
Reactant(Bromomethyl)cyclobutaneHCID 2734658—
SolventDimethylformamideHCID 6228—
ProductHCID 65457361HCID 6545736137.2%

Reaction Steps

4-Bromophenol (2.5 g, 14.5 mmol), (bromomethyl)cyclobutane (1.6 mL, 15 mmol), sodium hydroxide (0.8 g, 20 mmol) and DMF (3 mL) were allowed to react to yield the sub-title compound (1.3 g, 36%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-1d56950fb7fd4104928752ce6c6d8144
Source noteuspto-grants-2010_04