HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 56945267, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 45923264 | HCID 45923264 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 56945267 | HCID 56945267 | 97% |
Reaction Steps
2-(4-Bromophenoxy)-2-methylpropanoyl chloride (2.34 g, 8.4 mmol) in THF (10 mL) was added dropwise whilst stirring to anhydrous MeOH (1.34 g, 42 mmol), Et3N (1.7 g, 16.8 mmol) and THF at 0° C. The mixture was stirred at room temperature for 3 h, concentrated and distilled to afford the sub-title compound (1.74 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705023B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-a515af214adf4272be56060636005517 |
| Source note | uspto-grants-2010_04 |