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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646123Generated: October 29, 2026

Methanol → HCID 56945267, compound

https://huagongshe.com/reaction/646123

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantTriethylamineHCID 8471—
ReactantHCID 45923264HCID 45923264—
SolventTetrahydrofuranHCID 8028—
ProductHCID 56945267HCID 5694526797%

Reaction Steps

2-(4-Bromophenoxy)-2-methylpropanoyl chloride (2.34 g, 8.4 mmol) in THF (10 mL) was added dropwise whilst stirring to anhydrous MeOH (1.34 g, 42 mmol), Et3N (1.7 g, 16.8 mmol) and THF at 0° C. The mixture was stirred at room temperature for 3 h, concentrated and distilled to afford the sub-title compound (1.74 g, 97%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-a515af214adf4272be56060636005517
Source noteuspto-grants-2010_04