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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646126Generated: October 30, 2026

Ethyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylate → 5-(4-tert-Butylphenyl)-1-(4-(2-methyl-1-(pyrrolidin-1-yl)propan-2-yl-oxy)phenyl)indole-2-carboxylic acid

https://huagongshe.com/reaction/646126

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylateHCID 68475095—
Reactant1-(2-(4-Bromophenoxy)-2-methylpropyl)pyrrolidineHCID 68696686—
Product5-(4-tert-Butylphenyl)-1-(4-(2-methyl-1-(pyrrolidin-1-yl)propan-2-yl-oxy)phenyl)indole-2-carboxylic acidHCID 68701302—

Reaction Steps

The title compound was prepared in accordance with Example 1 using 5-(4-tert-butylphenyl)indole-2-carboxylic acid ethyl ester and 1-(2-(4-bromophenoxy)-2-methylpropyl)pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-ba33aac5bdd446289cb99d395ada2990
Source noteuspto-grants-2010_04