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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646147Generated: October 28, 2026

[6-(Propan-2-yloxy)pyridin-3-yl]boronic acid → 1-(6-Isopropoxypyrid-3-yl)-5-(5-trifluoromethylpyrid-2-yl)-1H-indole-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/646147

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[6-(Propan-2-yloxy)pyridin-3-yl]boronic acidHCID 44754864—
Reactant5-(5-trifluoromethylpyrid-2-yl)-1H-indole-2-carboxylic acid ethyl esterHCID 68472386—
Product1-(6-Isopropoxypyrid-3-yl)-5-(5-trifluoromethylpyrid-2-yl)-1H-indole-2-carboxylic acid ethyl esterHCID 68697357—

Reaction Steps

The sub-title compound was prepared in accordance with Example 8(c) from 5-(5-trifluoromethylpyrid-2-yl)-1H-indole-2-carboxylic acid ethyl ester (see Example 8(b)) and 6-isopropoxypyridine-3-boronic acid (see step (b) above).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-60d9a1ce081942799a164e815637e6a5
Source noteuspto-grants-2010_04