HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromophenol → 2-Bromoethyl p-bromophenyl ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromophenol | HCID 7808 | — |
| Reactant | 1,1-Dibromoethane | HCID 11201 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Bromoethyl p-bromophenyl ether | HCID 87797 | 83% |
Reaction Steps
A mixture of 4-bromophenol (30 g, 173 mmol), dibromoethane (40 mL, 464 mmol), NaOH (11.0 g, 275 mmol) and water (430 mL) was refluxed for 11 h. The phases were separated and the organic phase was further purified by distillation, yielding the sub-title compound (40.1 g 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705023B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-b4bef11246fe403980c687e7dbbb385f |
| Source note | uspto-grants-2010_04 |