2-Chloro-5-propylpyrimidine → 3-Chloro-1-(4-isopropoxyphenyl)-5-(5-propylpyrimidin-2-yl)-1H-indole-2-carboxylic acid

Participants

Reaction Steps

The title compound was prepared in accordance with Example 35, Method 1, step (d) from 3-chloro-1-(4-isopropoxyphenyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester (see Example 35, Method 1, step (c)) and 2-chloro-5-propylpyrimidine, followed by ester hydrolysis in accordance with Example 1(c).

Provenance & Evidence