Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646164Generated: October 30, 2026

(4-(Cyclopentyloxy)phenyl)boronic acid → 5-Bromo-3-chloro-1-(4-cyclopentyloxyphenyl)indole-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/646164

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-(Cyclopentyloxy)phenyl)boronic acidHCID 23005412—
Reactantethyl 5-bromo-3-chloro-1H-indole-2-carboxylateHCID 28330549—
Product5-Bromo-3-chloro-1-(4-cyclopentyloxyphenyl)indole-2-carboxylic acid ethyl esterHCID 68694787—

Reaction Steps

The sub-title compound was prepared in accordance with the procedure described in Example 8(c) using 5-bromo-3-chloro-1H-indole-2-carboxylic acid ethyl ester (see Example 3)5, Method 1, step (a)) and 4-cyclopentoxyphenylboronic acid instead of 4-isopropoxyphenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07705023B2
Source datasetuspto-grants-2010_04
ORD IDord-219f9106aef243439b0a979a77840710
Source noteuspto-grants-2010_04