HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-1-isopropoxy-2-nitrobenzene → 5-(4-tert-Butylphenyl)-1-(4-isopropoxy-3-nitrophenyl)-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-1-isopropoxy-2-nitrobenzene | HCID 22283241 | — |
| Reactant | Ethyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylate | HCID 68475095 | — |
| Product | 5-(4-tert-Butylphenyl)-1-(4-isopropoxy-3-nitrophenyl)-1H-indole-2-carboxylic acid | HCID 68698339 | — |
Reaction Steps
The title compound was prepared in accordance with Example 1(b) from 5-(4-tert-butylphenyl)indole-2-carboxylic acid ethyl ester (see Example 1(a)) and 4-bromo-1-isopropoxy-2-nitrobenzene (see step (a) above), followed by ester hydrolysis in accordance with the procedure described in Example 35, Method 3, step (b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705023B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-9662ac92284e4b43a547d8e9ce43070b |
| Source note | uspto-grants-2010_04 |