4-(Bromomethyl)benzonitrile → 3-[2-(4-Cyano-phenyl)-vinyl]-4-methoxy-benzamide

HRID 646394Notes

Reaction equation

HRID 646394 reaction equation
[C:1]([C:3]1[CH:10]=[CH:9][C:6]([CH2:7]Br)=[CH:5][CH:4]=1)#[N:2].[CH:11]([C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[C:16]([NH2:18])=[O:17])=O>>[C:1]([C:3]1[CH:10]=[CH:9][C:6]([CH:7]=[CH:11][C:13]2[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=2[O:22][CH3:23])[C:16]([NH2:18])=[O:17])=[CH:5][CH:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 869964-(Bromomethyl)benzonitrileHCID 231413863-Formyl-4-methoxybenzamide

Product 1

HCID 670026093-[2-(4-Cyano-phenyl)-vinyl]-4-methoxy-benzamide

Procedure

The captioned compound was synthesized from 4-cyanobenzyl bromide and 3-formyl-4-methoxybenzamide by the same procedure as in the manufacturing method described in Example 2-3-6.

Sources & evidence

ORD record
ord-0aa8c268e3094030b4ab7130cf756bc9
Source dataset
uspto-grants-2010_04
Patent number
US07705053B2

Reaction notes

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