Pyrrolidine → HCID 23141494, compound

HRID 646397Notes

Reaction equation

Br[C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[CH:4][C:3]=1/[CH:11]=[CH:12]/[C:13]1[CH:18]=[CH:17][C:16]([O:19][C:20]([F:23])([F:22])[F:21])=[CH:15][CH:14]=1.[NH:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1>>[N:24]1([C:2]2[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[CH:4][C:3]=2/[CH:11]=[CH:12]/[C:13]2[CH:18]=[CH:17][C:16]([O:19][C:20]([F:23])([F:22])[F:21])=[CH:15][CH:14]=2)[CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

Reactant 2

HCID 31268Pyrrolidine

HCID 23141402HCID 23141402, compound

Product 1

HCID 23141494HCID 23141494, compound

Procedure

The captioned compound was synthesized from 4-bromo-3-[(E)-2-(4-trifluoromethoxy-phenyl)-vinyl]-benzamide and pyrrolidine by the same procedure as in Example 2-5-2.

Sources & evidence

ORD record: ord-94dd5350777849029b6d1ac5ea8cfbd4
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07705053B2

Reaction notes

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