HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 178521105, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 178524231 | HCID 178524231 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178521105 | HCID 178521105 | — |
Reaction Steps
To a stirring solution of 4-(5-chloro-1H-benzoimidazol-2-yl)-benzoic acid (1.0 mmol) (CAS 204514-08-9) and oxalyl chloride (2.0 mmol) in dichloromethane (0.10M), add 2 drops of dimethylformamide as a catalyst. Stir at room temperature for 2 hours. After this time, concentrate the reaction in vacuo. Assume total conversion to the acid chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07705025B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-091098fe97404f5785376115cb8f1021 |
| Source note | uspto-grants-2010_04 |