Water → Decanoic Acid

HRID 646651Notes

Reaction equation

HRID 646651 reaction equation
[C:1](#N)[CH3:2].[O:4]1[CH2:8][CH2:7][CH2:6][CH2:5]1.[OH2:9]>>[OH:9][C:8]([CH2:7][CH2:6][CH2:5][CH2:5][CH2:6][CH2:7][CH2:8][CH2:1][CH3:2])=[O:4]

Participants

4

Reactant 3

HCID 962WaterHCID 6342AcetonitrileHCID 8028Tetrahydrofuran

Product 1

HCID 2969Decanoic Acid

Procedure

Instrumentation: Preparative HPLC (Waters 4000) equipped with refractive index monitor (Waters 2414) and a radial compression module (Waters 8×100). A preparative C18 column (Nova-Pak HR 8×100) was used with a Shimadzu CR 501 chromatopac integrator. The mobile phase was prepared by mixing acetonitrile with tetrahydrofuran and water in a ratio of 5:1:4.

Workup

  1. customInstrumentation: Preparative HPLC (Waters 4000) equipped with refractive index monitor (Waters 2414)
  2. customThe mobile phase was prepared

Sources & evidence

ORD record
ord-049f699773d8474b8d70a87031cf3c33
Source dataset
uspto-grants-2010_04
Patent number
US07705169B2

Reaction notes

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