Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 646728Generated: October 30, 2026

HCID 68650633, compound → HCID 59407593, compound

https://huagongshe.com/reaction/646728

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68650633HCID 68650633—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 59407593HCID 5940759394.8%

Reaction Steps

To a solution of 5-(hydroxyprop-1-yn-1-yl)-2,3-dihydro-1H-indene-1-one (1.06 g, 5.71 mmol) in MeOH was added 10% Pd/C and hydrogenated by means of Pair shaker. After 12 h, the reaction mixture was filtered on Celite and concentrated in vacuo to give 5-(3-hydroxypropyl)-2,3-dihydro-1H-inden-1-one (1.03 g, 94% yield): MS (EI) for C12H14O2: 191.24 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07704995B2
Source datasetuspto-grants-2010_04
ORD IDord-bc32c1a08c124fb9b06431b99bcd9024
Source noteuspto-grants-2010_04