HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 131714841, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 3-Bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine | HCID 13712154 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 131714841 | HCID 131714841 | — |
Reaction Steps
0.23 g (0.93 mMol) 3-bromo-6-chloro-2-methyl-imidazo[1,2-b]pyridazine obtained from Example 1 is dissolved in 2 ml concentrated acetic acid and treated with 1.39 mMol elemental bromine. From the reaction mixture crystallizes out after a little while 3-bromo-6-chloro-2-methyl-imidazo[1,2-b]pyridazine dibromide. This is filtered off and dried. Yield 0.38 g, (89.4%), M.pt 217°-220°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04609731 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-da451269977943ada234786154e6e0cf |
| Source note | uspto-grants-1986_09 |