Hydrochloric Acid → Methyl 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]propanimidate

HRID 64677Notes

Reaction equation

[C:1]([CH2:3][CH2:4][S:5][CH2:6][C:7]1[N:8]=[C:9]([N:12]=[C:13]([NH2:15])[NH2:14])[S:10][CH:11]=1)#[N:2].Cl.[CH2:17]=[O:18]>>[NH2:15][C:13](=[N:12][C:9]1[S:10][CH:11]=[C:7]([CH2:6][S:5][CH2:4][CH2:3][C:1](=[NH:2])[O:18][CH3:17])[N:8]=1)[NH2:14]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 712Formaldehyde

HCID 50752593-(2-(Diaminomethyleneamino)thiazol-4-yl)methylthio)propiononitrile

Product 1

HCID 12881442Methyl 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]propanimidate

Procedure

reacting the compound produced in step (b) with hydrogen chloride and methanal to obtain the compound methyl 3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propionimidate isolating and drying said compound; and

Sources & evidence

ORD record: ord-5a1e6b2a0e6647e7930c01bfbef2b1d7
Source dataset: uspto-grants-1986_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04609737

Reaction notes

Loading…