4-Chlorophenyl isothiocyanate → HCID 13191291, compound

Participants

Reaction Steps

A mixture of 5.8 g. of 3-(4-difluoromethoxyphenyl)-4-phenyl-2-pyrazoline and 3.4 g. of 4-chlorophenylisothiocyanate in 200 ml. of anhydrous ethyl ether was refluxed for 6 hours to react them. After cooling the reaction mixture, the precipitated crystal (6.1 g.) was separated by a filtration. It was confirmed that the product was 1-(4-chlorophenylthiocarbamoyl)-3-(4-difluoromethoxyphenyl)-4-phenyl-2-pyrazoline (melting point of 158.0°-161.0° C.) by the NMR spectrum.

Provenance & Evidence