反应详情

To a stirred solution of 5-amino-2-naphthol (8.0 g, 0.05 mol) in pyridine (80 ml) was added the sulfonyl chloride, N,N-dioctadecyl-3-chlorosulfonylbenzamide (Example 5) (36.2 g, 0.05 mol). The reaction was stirred overnight at room temperature and then poured into excess dilute hydrochloric acid. The mixture was extracted with dichloromethane, washed with water, dried over magnesium sulfate and suction-filtered through a pad of decolorizing carbon. The filtrate was concentrated to an oil which was crystallized from acetonitrile to yield 26.5 g of product.

1. extractionThe mixture was extracted with dichloromethane
2. washwashed with water
3. dry with materialdried over magnesium sulfate
4. filtrationsuction-filtered through a pad of decolorizing carbon
5. concentrationThe filtrate was concentrated to an oil which
6. customwas crystallized from acetonitrile