Potassium Carbonate → HCID 12770718, compound

Participants

Reaction Conditions

Reaction Steps

27.3 g (0.2 mole) of 2-acetoxyacetyl chloride were added to a mixture of 33.1 g (0.24 mole) of potassium carbonate, 200 ml of acetonitrile and 29.4 g (0.2 mole) of N-isopropyl-O-(2-ethoxyethyl)-hydroxylamine. During this addition, the temperature increased to about 30° C. The reaction mixture was subsequently stirred for a further 2 hours, without cooling, and was filtered and the solvent was distilled off in vacuo. 38 g (77% of theory) of acetoxy-acetic acid N-(2-ethoxyethoxy)-N-isopropyl-amide were thus obtained in the form of a colourless oil with a boiling point of 106°-107° C./0.1 mm Hg.

Provenance & Evidence