Hydrochloric Acid → HCID 12461092, compound

HRID 647359Notes

Reaction equation

HRID 647359 reaction equation
[S:1]([O:5][CH2:6][CH:7]1[O:9][CH2:8]1)([CH3:4])(=[O:3])=[O:2].[ClH:10]>>[S:1]([O:5][CH2:6][CH:7]([OH:9])[CH2:8][Cl:10])([CH3:4])(=[O:3])=[O:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 110799(Oxiran-2-yl)methyl methanesulfonate

Product 1

HCID 12461092HCID 12461092, compoundYield 85%

Procedure

Concentrated HCl (20 ml) was added to 3-mesyloxy-1,2-epoxypropane (5.0 g, 0.033 m) over 15-20 minutes. After stirring for an additional 30 minutes, the water was removed through the addition and subsequent evaporation of ethanol. Finally, residual ethanol was removed at room temperature and 0.1 mm to give 3-mesyloxy-2-hydroxy-1-chloropropane (5.4 g, 85%).

Workup

  1. customthe water was removed through the addition and subsequent evaporation of ethanol
  2. customFinally, residual ethanol was removed at room temperature

Sources & evidence

ORD record
ord-ade210d874114f9ab983ba9f6483e577
Source dataset
uspto-grants-1983_10
Patent number
US04408063

Reaction notes

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