HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 13252420, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 20484937 | HCID 20484937 | — |
| Product | HCID 13252420 | HCID 13252420 | 81.2% |
Reaction Steps
By the same procedure as described in Method (a) of Example 1, 55.0 g of 2-(4-bromo-2-fluorophenyl)-2,3,4,5,6,7-hexahydro-3-thioxo-1H-isoindol-1-one was reduced with 18.0 g of sodium borohydride, thereby affording 44.9 g (yield of 81%) of the subject compound. Recrystallization from ethanol yielded white crystals, m.p. 87°-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04409018 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-3b033f10aa034289ade728507d9731f0 |
| Source note | uspto-grants-1983_10 |