Triethylamine → HCID 12834418, compound

HRID 647499Notes

Reaction equation

HRID 647499 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6](C)=[CH:7][CH:8]=[C:9](CBr)[CH:10]=1)=[O:4].[SH:14][C:15]1[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=1.[CH2:21](N(CC)CC)C>C1(C)C=CC=CC=1>[N:18]1[CH:19]=[CH:20][C:15]([S:14][CH2:21][C:8]2[CH:9]=[CH:10][C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:6][CH:7]=2)=[CH:16][CH:17]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 86212244501362-17-0HCID 178418431pyridine-4-thiol

Product 1

HCID 12834418HCID 12834418, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture containing 11.0 grams of methyl-p-(bromomethyl)toluate (0.048 mole), 5.3 grams of 4-mercaptopyridine (0.048 mole), 25 ml of triethylamine and 200 ml of toluene was refluxed for 16 hours and then cooled to room temperature. The reaction mixture was washed twice with 300 ml of water. The toluene layer was dried over anhydrous sodium sulfate and then concentrated to give a dark red oil which solidified upon cooling.

Workup

  1. temperaturewas refluxed for 16 hours
  2. washThe reaction mixture was washed twice with 300 ml of water
  3. dry with materialThe toluene layer was dried over anhydrous sodium sulfate
  4. concentrationconcentrated
  5. customto give a dark red oil which
  6. temperatureupon cooling

Sources & evidence

ORD record
ord-9a5f9e91fcb74971a95b4c77a3c02bd9
Source dataset
uspto-grants-1983_10
Patent number
US04409227

Reaction notes

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