HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Acetamido-1-[6-(2,2,2-trifluoro) ethoxy-2-pyridyl]piperidine | HCID 12926619 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 12760111 | HCID 12760111 | — |
Reaction Steps
By heating the 4-acetamido-1-[6-(2,2,2-trifluoro) ethoxy-2-pyridyl]piperidine at reflux for 3 hours in an 0.5 N solution of hydrochloric acid and then operating as described in Example 1, the monohydrochloride of 4-amino-1-[6-(2,2,2-trifluoro)ethoxy-2-pyridyl] piperidine (CM 57385) is obtained which, after crystallation in ethanol, melts at 218° to 225° C. with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04409228 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-eea95c5ddc35469da0b268a02c0425cf |
| Source note | uspto-grants-1983_10 |