HCID 20278223, compound → HCID 20278240, compound

HRID 647531Notes

Reaction equation

HRID 647531 reaction equation
[C:1]([N:4]1[CH2:9][CH2:8][C:7]2([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[CH:11]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[S:10]2)[CH2:6][CH2:5]1)(=O)[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[CH2:1]([N:4]1[CH2:9][CH2:8][C:7]2([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[CH:11]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[S:10]2)[CH2:6][CH2:5]1)[CH3:2]

Participants

4

Reactant 2

HCID 20278223HCID 20278223, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20278240HCID 20278240, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A solution of 1'-acetyl-1,3-dihydro-3-phenylspiro[benzo(c)thiophene-1,4'-piperidine], Example 10, in tetrahydrofuran is treated carefully with a stirred suspension of lithium aluminum hydride in tetrahydrofuran to provide 1'-ethyl-1,3-dihydro-3-phenylspiro[benzo(c)thiophene-1,4'-piperidine].

Sources & evidence

ORD record
ord-4d28c0163fcb41cdaf95ce3a3f70efcc
Source dataset
uspto-grants-1983_10
Patent number
US04409229

Reaction notes

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