3-AMino-butyronitrile → HCID 20237378, compound

HRID 64759Notes

Reaction equation

HRID 64759 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([S:8]([CH:11]([CH3:13])[CH3:12])(=[O:10])=[O:9])[CH:5]=[CH:4][C:3]=1[O:14][C:15]1[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[C:17]([N+:24]([O-])=O)[CH:16]=1.N[CH:28]([CH3:32])[CH2:29][C:30]#[N:31]>C(#N)C>[N+:21]([C:18]1[CH:19]=[CH:20][C:15]([O:14][C:3]2[CH:4]=[CH:5][C:6]([S:8]([CH:11]([CH3:12])[CH3:13])(=[O:10])=[O:9])=[CH:7][C:2]=2[Cl:1])=[CH:16][C:17]=1[NH:24][CH:28]([CH3:32])[CH2:29][C:30]#[N:31])([O-:23])=[O:22]

Participants

4

Reactant 2

HCID 1233663-AMino-butyronitrileHCID 202373452-Chloro-4-isopropylsulphonyl-(3,4-dinitrophenoxy)benzene

Product 1

HCID 20237378HCID 20237378, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of 4.0 g of 2-chloro-4-isopropylsulphonyl-(3,4-dinitrophenoxy)benzene and 2,5 g of 3-aminobutyronitrile in 30 ml of acetonitrile was refluxed for 13 hours. After evaporation the residue was recrystallized from methanol. The desired product was obtained in a yield of 3.3 g; m.p. 132° C.

Workup

  1. customAfter evaporation the residue
  2. customwas recrystallized from methanol

Sources & evidence

ORD record
ord-f14fe54d8cae4be49a411ae0a37b6218
Source dataset
uspto-grants-1986_09
Patent number
US04609753

Reaction notes

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