反应详情

To 30 ml of N-methylpyrrolidone, 1 g of 1-amino-2-mercapto-4-hydroxyanthraquinone, 1.2 g of trans-4-n-penthylcyclohexylmethyl bromide and 0.6 g of sodium carbonate were added. The resulting mixture was heated at 120° to 125° C. for 7 hours. After cooling to 60° to 70° C., the mixture was poured on 100 g of ice, followed by separation of the product and washing with water until neutral was obtained. The product thus obtained was dried and purified by column chromatography using silica gel as carrier and chloroform as separating solvent to give 0.7 g of 1-amino-2-(trans-4-n-pentylcyclohexylmethylmercapto)-4-hydroxyanthraquinone having a melting point of 129°-130° C.

1. temperatureThe resulting mixture was heated at 120° to 125° C. for 7 hours
2. temperatureAfter cooling to 60° to 70° C.
3. customfollowed by separation of the product
4. washwashing with water
5. customuntil neutral was obtained
6. customThe product thus obtained
7. customwas dried
8. custompurified by column chromatography
9. customas separating solvent