反应详情

A suspension of 3.11 g. of 1,4-dihydroxy-5,8-bis[[2-(2-hydroxyethylamino)ethyl]amino]anthraquinone [prepared as described in Example 1(A)] in 55.0 ml. of benzene containing 2.02 g. of 2-furaldehyde is stirred and heated under reflux using a Dean-Stark trap. A total of 0.2 ml. of water is collected as distillate over a 3 hour period, with no additional water after a total of 7 hours of refluxing. The hot solution is filtered, removing a small amount of blue-black solid. The filtrate is concentrated and petroleum ether is added to give a gum which slowly solidifies. The solid is collected and washed with benzene to give 2.05 g. of a blue-black solid.

1. additionA suspension of 3.11 g
2. temperatureheated
3. temperatureunder reflux
4. distillationof water is collected as distillate over a 3 hour period, with no additional water after a total of 7 hours
5. temperatureof refluxing
6. filtrationThe hot solution is filtered
7. customremoving a small amount of blue-black solid
8. concentrationThe filtrate is concentrated
9. additionpetroleum ether is added
10. customto give a gum which
11. customThe solid is collected
12. washwashed with benzene
13. customto give 2.05 g