HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Pyrrol-2-yl-carbonyl-L-leucyl-glycinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Pyrrole-2-Carboxylic Acid | HCID 12473 | — |
| Reactant | Glycinamide, L-leucyl- | HCID 6993103 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Pyrrol-2-yl-carbonyl-L-leucyl-glycinamide | HCID 53906830 | — |
Reaction Steps
7.0 ml of triethylamine and 10.4 g of the N-hydroxysuccinimide ester of pyrrole-2-carboxylic acid were added to 9.4 g of L-leucyl-glycinamide in 120 ml of dioxane at 10° C. and the reaction mixture was stirred for 2 hours at this temperature, after which 30 ml of water were added and the stirred mixture was allowed to react for 20 hours at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04610818 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-5909ef2253f94ad1805d16a92c4d454f |
| Source note | uspto-grants-1986_09 |