Veratrole → 4-(3,4-Dimethoxybenzoyl)-5-ethyl-2-imidazolidinone

Participants

Reaction Conditions

Reaction Steps

In 100 g PPA are suspended 15.8 g 4-ethyl-2-oxoimidazolidine-5-carboxylic acid and 13.8 g 1,2-dimethoxybenzene. The mixture is rapidly stirred and heated for 5 hours at 100° C. The reaction mixture is quenched with water and the product separates as a solid. The solid is collected and washed with water and dried. Purification is effected by chromatography over silica gel.

Provenance & Evidence