Acetic Acid → HCID 20484279, compound

Participants

Reaction Steps

4.5 g of 5-hydrazino-3-methylbenzothiophene-2-carboxylic acid benzyl ester hydrochloride are suspended in a mixture of HCl and glacial acetic acid; after adding 3 ml of 1-methyl-4-piperidone, the reaction mixture is boiled for 3 hours. The solvent is then evaporated off and the residue is adjusted to pH 7.5, and worked up as described under Example 11. Melting point: 174° C.

Provenance & Evidence