HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 6,9-Bis-(3-dimethylaminopropyl)-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole trimaleate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Chloro-N,N-dimethyl-1-propanamine | HCID 66960 | — |
| Reactant | Maleate(2-) | HCID 5288227 | — |
| Reactant | 9-(3-Dimethylaminopropyl)-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole | HCID 20484312 | — |
| Product | 6,9-Bis-(3-dimethylaminopropyl)-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole trimaleate | HCID 86739087 | — |
Reaction Steps
The compound is formed analogously to that described in Example 31, from 5 g of 9-(3-dimethylaminopropyl)-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole, NaH and 3-dimethylaminopropyl chloride indimethylformamide, the product subsequently being converted into the maleate. Melting point: 174° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04410536 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-5b3696d082e94bbd81483dde324a9336 |
| Source note | uspto-grants-1983_10 |