HRID647949

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24758

Sodium hydride

HNa

HCID66960

Dimethylaminopropyl chloride

C5H12ClN

$结构：O=C([O-])/C=C\C(=O)[O-]$

HCID5288227

Maleate (2-)

C4H2O4-2

结构：Cc1csc2ccc3[nH]c4c(c3c12)CN(CCCN(C)C)CC4

HCID20484312

未命名化合物

PRODUCTS

生成物

$结构：Cc1csc2ccc3c(c4c(n3CCCN(C)C)CCN(CCCN(C)C)C4)c12.O=C(O)/C=C\C(=O)O.O=C(O)/C=C\C(=O)O.O=C(O)/C=C\C(=O)O$

HCID86739087

未命名化合物

PROCEDURE

实验过程

The compound is formed analogously to that described in Example 31, from 5 g of 9-(3-dimethylaminopropyl)-1-methyl-7,8,9,10-tetrahydrothieno[3,2-e]pyrido[4,3-b]indole, NaH and 3-dimethylaminopropyl chloride indimethylformamide, the product subsequently being converted into the maleate. Melting point: 174° C.

WORKUP

后处理

customThe compound is formed analogously to

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5b3696d082e94bbd81483dde324a9336
来源数据集: uspto-grants-1983_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04410536
来源说明: uspto-grants-1983_10

反应 SMILES

[CH3:1][N:2]([CH3:23])[CH2:3][CH2:4][CH2:5][N:6]1[CH2:22][CH2:21][C:9]2[NH:10][C:11]3[C:16]([C:8]=2[CH2:7]1)=[C:15]1[C:17]([CH3:20])=[CH:18][S:19][C:14]1=[CH:13][CH:12]=3.[H-].[Na+].[CH3:26][N:27]([CH3:32])[CH2:28][CH2:29][CH2:30]Cl.[C:33]([O-:40])(=[O:39])/[CH:34]=[CH:35]\[C:36]([O-:38])=[O:37]>>[C:33]([OH:40])(=[O:39])/[CH:34]=[CH:35]\[C:36]([OH:38])=[O:37].[C:33]([OH:40])(=[O:39])/[CH:34]=[CH:35]\[C:36]([OH:38])=[O:37].[C:33]([OH:40])(=[O:39])/[CH:34]=[CH:35]\[C:36]([OH:38])=[O:37].[CH3:26][N:27]([CH3:32])[CH2:28][CH2:29][CH2:30][N:10]1[C:11]2[C:16](=[C:15]3[C:17]([CH3:20])=[CH:18][S:19][C:14]3=[CH:13][CH:12]=2)[C:8]2[CH2:7][N:6]([CH2:5][CH2:4][CH2:3][N:2]([CH3:1])[CH3:23])[CH2:22][CH2:21][C:9]1=2