HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 5-(2-Methoxyethyl)pyrimidine-2,4(1H,3H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 2-(2,4-dioxo-1H-pyrimidin-5-yl)ethyl methanesulfonate | HCID 10243099 | — |
| Product | 5-(2-Methoxyethyl)pyrimidine-2,4(1H,3H)-dione | HCID 15276926 | — |
Reaction Steps
6.0 g of 5-(2-methylsulphonyloxyethyl)-uracil are suspended in 100 ml of absolute methanol and the suspension is heated to 120°-130° C. for one hour in a pressure vessel. After cooling to room temperature, the crystals obtained are filtered off and washed with methanol. 5-(2-Methoxyethyl)-uracil, melting point 232°-234° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04410530 |
| Source dataset | uspto-grants-1983_10 |
| ORD ID | ord-672667864e3f484699991502dddbbab1 |
| Source note | uspto-grants-1983_10 |