Boron trifluoride etherate → HCID 12740028, compound

HRID 648118Notes

Reaction equation

HRID 648118 reaction equation
B(F)(F)F.CC[O:7]CC.[CH2:10]([C:17]1[CH:22]=[C:21]([CH2:23][C:24](Cl)=[O:25])[CH:20]=[CH:19][C:18]=1[CH2:27][C:28](Cl)=[O:29])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>ClC(Cl)C>[O:29]=[C:28]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[CH2:10][C:17]2[CH:22]=[C:21]([CH2:23][C:24]([OH:7])=[O:25])[CH:20]=[CH:19][C:18]=2[CH2:27]1

Participants

4

Reactant 2

HCID 8000Boron trifluoride etherateHCID 53966163HCID 53966163, compound

Product 1

HCID 12740028HCID 12740028, compound

Reagents, catalysts & solvents 1

HCID 63651,1-DichloroethaneSolvent

Procedure

In 50 ml of dichloroethane was dissolved in 3.0 g of 2-benzyl-4-chlorocarbonylmethylphenylacetyl chloride. With stirring at room temperature, 5.0 g of a solution of boron trifluoride etherate was added to the solution. The mixture was stirred for 2 hours, and worked up in the same way as in Example 6 to afford 1.42 g of 10,11-dihydro-10-oxo-5H-dibenzo[a,d]cycloheptene-3-acetic acid as a colorless crystalline powder (recrystallized from a mixture of methanol and n-hexane) having a melting point of 186° to 188° C.

Workup

  1. stirringThe mixture was stirred for 2 hours

Sources & evidence

ORD record
ord-1e803c3776e44056b83093ddfd004699
Source dataset
uspto-grants-1983_10
Patent number
US04410716

Reaction notes

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