Boron trifluoride etherate → HCID 12740028, compound

Participants

Reaction Steps

In 50 ml of dichloroethane was dissolved in 3.0 g of 2-benzyl-4-chlorocarbonylmethylphenylacetyl chloride. With stirring at room temperature, 5.0 g of a solution of boron trifluoride etherate was added to the solution. The mixture was stirred for 2 hours, and worked up in the same way as in Example 6 to afford 1.42 g of 10,11-dihydro-10-oxo-5H-dibenzo[a,d]cycloheptene-3-acetic acid as a colorless crystalline powder (recrystallized from a mixture of methanol and n-hexane) having a melting point of 186° to 188° C.

Provenance & Evidence