Hydrazine → HCID 20482388, compound

HRID 648186Notes

Reaction equation

HRID 648186 reaction equation
C1(=O)[N:5]([CH2:6][CH:7]([OH:20])[CH2:8][O:9][C:10]2[S:11][C:12]([C:15](=[O:19])[N:16]([CH3:18])[CH3:17])=[CH:13][N:14]=2)C(=O)C2=CC=CC=C12.NN>C(O)C>[NH2:5][CH2:6][CH:7]([OH:20])[CH2:8][O:9][C:10]1[S:11][C:12]([C:15](=[O:19])[N:16]([CH3:17])[CH3:18])=[CH:13][N:14]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 20482357HCID 20482357, compound

Product 1

HCID 20482388HCID 20482388, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product from Example 9 (4.0 g, 10.6 mmol) can be added to a solution of hydrazine (0.38 g, 12 mmol) in absolute ethanol (20 ml) and the suspension refluxed 4 hours under nitrogen on a steam bath. The mixture can then be cooled and filtered and the filtrate concentrated in vacuo to give the title compound as an oil.

Workup

  1. temperaturethe suspension refluxed 4 hours under nitrogen on a steam bath
  2. temperatureThe mixture can then be cooled
  3. filtrationfiltered
  4. concentrationthe filtrate concentrated in vacuo

Sources & evidence

ORD record
ord-7f7258c5c4c64b00a8ebd2ddeca99bf9
Source dataset
uspto-grants-1983_10
Patent number
US04411899

Reaction notes

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