Butyl Chloride → Butyl ether

Participants

Reaction Steps

To a 1-liter flask equipped with a stirrer, a reflux condenser and a dropping funnel was added magnesium chip (12 g) for Grignard reagent. After replacing atmosphere in the flask by argon, di-n-butyl ether (250 ml) was added, and then n-butyl chloride (62 ml, 1.2 times by mole based on magnesium) was added dropwise to start reaction with the contents of the falsk kept at 50° C. After addition over 2 hours at 50° C., reaction was continued at this temperature for further 5 hours to obtain a di-n-butyl ether solution of n-butylmagnesium chloride. The concentration of this solution was 1.45 mole/liter.

Provenance & Evidence